The Takeaway The results of this study suggest a unique sensitivity to alveolar hyperoxia at the time of lung reinflation and raise the possibility that restricting the inspired oxygen fraction during lung reinflation could reduce injury and related sequelae. Our findings imply that a 10% increase in FiO2 during the
The Takeaway Intraperitoneal dexamethasone, dexmedetomidine, and their combination reduce postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy Study Design * Prospective randomized triple-blind study * 240 patients aged 20–50 years, ASA Class I or II * Exclusion criteria were a history of psychotic illnesses, Parkinson’s disease, motion disorder, and a history
IOH
To reduce cardiac, renal, and neurological complications, targeting MAP >65 mmHg is a reasonable threshold for most patients. However, individualized BP management is crucial, especially for high-risk patients.
hepatectomy
Tranexamic acid can help reduce blood transfusions in hepatectomy without added risk, although more studies are needed to refine dosing and safety profiles.
The Takeaway Patients with Chronic Kidney Disease who were given rocuronium and reversed with sugammadex had a significantly higher risk for acute cardiovascular and pulmonary complications when compared to patients who were administered cisatracurium plus neostigmine Study Design * Retrospective observational study * Propensity-matched study including 20,548 patients with CKD Physiology
The Takeaway The opioid free regimen reduced the overall incidence of PONV and reduced the risk of developing first postoperative PONV compared to standard opioid-based general anesthesia - without an increase in pain scores at rest or with movement after surgery. Study Design * blinded, randomized, parallel-group trial * 168 patients aged
Takeaway A bolus of 1.5 mg/kg, followed by an infusion of 2 mg/kg/h until the end of the surgery can help reduce postoperative laryngopharyngeal symptoms, including sore throat, hoarseness, and cough, without increasing adverse reactions. Design * Prospective, randomized, double-blind, controlled, single-center clinical trial with 160 patients.
pulmonary complications
“In planned open heart surgery, use of DBEs with IS in the preop period may contribute to a reduced PPCs, duration of MV, length of ICU stay, duration of hospitalisation, and improved in pre- and postop oxygenation”
delirium
Conventional wisdom suggests that benzodiazepines increase delirium risk in the elderly. Although they remain on the Beer’s list as a high risk prescription medication, this recent study suggests that perioperative use does not increase risk of postoperative delierium.
fluid management
When Hurricane Helene ravaged North Carolina in 2024, it also took out Baxter’s ability to provide 60% of the United States’ intravenous fluid supplies. Despite significant changes in fluid management strategies, there were no changes in patient outcomes.
acetaminophen
What if a commonly used analgesic isn’t as effective as we think?
lidocaine
A lidocaine induction dose followed by infusion can reduce propofol requirements, leading to decreased desaturation episodes, coughing, involuntary movement, and improved endoscopist satisfaction
